Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp86 | Thyroid Nodules and Cancer | ECE2019

Benefits and limitations of TKIs in patients with medullary thyroid cancer: a systematic review and meta-analysis

Efstathiadou Zoe , Tsentidis Charalambos , Bargiota Alexandra , Daraki Vasiliki , Kotsa Kalliopi , Ntali Georgia , Papanastasiou Lamprini , Tigas Stylianos , Toulis Konstantinos , Pazaitou-Panayiotou Kalliopi , Alevizaki Maria

Tyrosine Kinase Inhibitors (TKIs) have been used in patients with advanced Medullary Thyroid Carcinoma (MTC). However, for some compounds, data on effectiveness and safety are limited. The aim of this systematic review and meta-analysis was to document clinical response and toxicities of TKIs in advanced MTC.Methods: A literature search in MEDLINE, EMBASE and Cochrane until May 2018 was performed for articles or abstracts on TKI use in MTC. Studies were ...